منابع مشابه
Improving the quality of antibiotic prescribing in the NHS by developing a new Antimicrobial Stewardship Programme: Start Smart--Then Focus.
There has been dramatic change in antibiotic use in English hospitals. Data from 2004 and 2009 show that the focus on reducing fluoroquinolone and second- and third-generation cephalosporin use seems to have been heeded in NHS secondary care, and has been associated with a substantial decline in hospital Clostridium difficile rates. However, there has been a substantial increase in use of co-am...
متن کاملAntibiotic policies in acute English NHS trusts: implementation of 'Start Smart-Then Focus' and relationship with Clostridium difficile infection rates.
OBJECTIVES The objective of this study was to establish how antibiotic prescribing policies at National Health Service (NHS) hospitals match the England Department of Health 'Start Smart-Then Focus' recommendations and relate to Clostridium difficile infection (CDI) rates. METHODS Antibiotic pharmacists were surveyed regarding recommendations for empirical treatment of common syndromes ('Star...
متن کاملSmart "Predict, then Optimize"
Many real-world analytics problems involve two significant challenges: prediction and optimization. Due to the typically complex nature of each challenge, the standard paradigm is to predict, then optimize. By and large, machine learning tools are intended to minimize prediction error and do not account for how the predictions will be used in a downstream optimization problem. In contrast, we p...
متن کاملImplementation of antimicrobial stewardship interventions recommended by national toolkits in primary and secondary healthcare sectors in England: TARGET and Start Smart Then Focus.
OBJECTIVES To assess and compare the implementation of antimicrobial stewardship (AMS) interventions recommended within the national AMS toolkits, TARGET and Start Smart Then Focus, in English primary and secondary healthcare settings in 2014, to determine the prevalence of cross-sector engagement to drive AMS interventions and to propose next steps to improve implementation of AMS. METHODS E...
متن کاملModel-based Clustering With an Adaptive Mixtures Smart Start
This paper details a new clustering methodology that is based on the use of a semi-parametric density estimation procedure, called adaptive mixtures density estimation, as a “smart start” to a standard model-based clustering approach. This technique allows one to process large datasets without the necessity of precomputation of the interpoint distance matrix which is inherently an O(n) operatio...
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ژورنال
عنوان ژورنال: British Dental Journal
سال: 2020
ISSN: 0007-0610,1476-5373
DOI: 10.1038/s41415-020-1751-z